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CLINICAL TRIALS | EVALUATIONS

Clinical Trials and Sponsored Translational Research

The Clinical Microbiology program at Beth Israel Deaconess Medical Center has extensive experience partnering with industry sponsors to perform regulatory-grade evaluations of diagnostic devices and assays. We serve as a clinical trial and method evaluation site for manufacturers developing new clinical microbiology diagnostics, including studies designed to support FDA clearance and approval.

Our group routinely conducts sponsor-initiated and investigator-initiated performance studies under institutional and regulatory oversight, and we are well positioned to participate as a clinical trial site for 510(k), PMA, and other FDA-directed submissions. We have experience operating under master services agreements (MSAs) and collaborating with regulatory, clinical affairs, and assay development teams.

Capabilities and Expertise
  • Evaluation of molecular, culture-based, and phenotypic diagnostic platforms
  • Clinical performance studies supporting FDA submissions
  • Experience with method comparison, specimen type validation, and workflow assessment
  • Access to diverse, contemporary clinical isolate collections, including bacteria, fungi, and emerging resistance phenotypes
  • Expertise in antimicrobial susceptibility testing and resistance characterization
  • Ability to support prospective and retrospective study designs
Our laboratory has completed multiple high-impact diagnostic evaluations, including studies of alternative specimen types, swab and collection devices, and novel assay platforms. These efforts have resulted in peer-reviewed publications and have informed regulatory and clinical adoption of new diagnostic technologies.

Translational Research and Antimicrobial Evaluation
In addition to diagnostic device trials, we develop and maintain well-characterized bacterial strain sets for evaluation of new antimicrobial agents. We collaborate with pharmaceutical and biotechnology partners to test novel compounds against in-house collections representing clinically relevant and resistant pathogens, supporting translational research and early development decisions.

Industry Collaboration

We welcome inquiries from diagnostic and biotechnology companies interested in:
  • Clinical trial site participation
  • Sponsored performance evaluations
  • Regulatory-directed studies
  • Long-term collaborations under MSAs

For discussions regarding diagnostic trials, regulatory studies, or translational research collaborations, please contact:
Stefan Riedel, MD, PhD
Clinical Microbiology
Beth Israel Deaconess Medical Center
📧 [email protected]

You may also contact James Kirby, MD ([email protected]).
Please indicate that you were referred via clinmicrolab.org.

BLOG
  • Home
  • Faculty
  • Fellowship
    • Collaborative Training >
      • Beth Israel Deaconess Medical Center
      • Boston Children's Hospital
      • State Laboratory Institute
    • Training Pathways
    • Philosophy, Goals, and Organization
    • Relationship to Pathology Department
    • Laboratory-Based Training
    • Infectious Disease Training
    • Laboratory Management
    • Graded Responsibility
    • Role of Fellows in Conferences
    • Weekly Schedule
    • SUMMARY PATHWAYS, CERTIFICATIONS, APPLICATION CONTACTS
    • Current and Former Fellows
  • Apply Here
  • PUBLICATIONS
  • RESEARCH OPPORTUNITIES
  • CYTOGENETICS POSITIONS
  • Clinical Trials
  • Blog
  • Resources