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Learning to Count the Hard Way: Measuring Diversity in the Microbiome and Beyond
presented by: Ramy Arnaout, MD, DPhil Dr. Arnaout is the Associate Director of the Clinical Microbiology Laboratories at Beth Israel Deaconess Medical Center and Associate Professor of Pathology at Harvard Medical School and President of the ASM Northeast Branch. His research lies at the intersection of computation, immunology, and infectious disease and brings mathematical and physics-based approaches to bear on several problems, including deciphering large-scale antibody and T-cell receptor immunomes. Today’s talk is about a key tool in the toolkit: measuring diversity in complex systems. Learning to do so led the laboratory on an enlightening (and humbling) journey from immunomes to information theory to microbiomes and beyond. Staking out new territory on the ribosome for antibiotic development presented by: James E. Kirby, MD, D(ABMM) Dr. Kirby is an NIH-funded Principal Investigator in the Experimental Pathology Division of Beth Israel Deaconess Medical Center, Boston, MA, Director of the Clinical Microbiology Laboratory at BIDMC; Program Director of the Medical Microbiology Fellowships at BIDMC; and Professor of Pathology at Harvard Medical School, Boston, MA. He was past president of the Northeast Branch-ASM from 2009-2012. Dr. Kirby will talk about his collaborative efforts to develop antibiotics targeting gram-negative ESKAPE pathogens. He will discuss the emerging threat from such pathogens; the difficulty in developing new drugs to treat them; and the activity; action; and goals and strategies for development of rediscovered natural products. Registration
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